Single Anastomosis Duodeno-Ileal Switch (SADIS): a promising alternative procedure for weight loss and comorbidity resolution.

Due to risk of weight regain and comorbidities after Sleeve Gastrectomy (SG) and Roux-en-Y Gastric Bypass operations, bariatric surgeons have been looking for alternative methods. The Single-Anastomosis Duodeno-Ileal Switch (SADIS) is a potential alternative. However, limited research has been done on the postoperative outcome of this type of operation. Therefore, a comprehensive literature review was performed, analyzing data on weight loss, comorbidity risks and nutritional deficiencies.

Efficacy of SADIS

The efficacy of SADIS was defined as the weight loss outcome and comorbidity resolution. SADIS had promising outcomes for weight loss: the average percentage of excess weight loss after SADIS ranged from 30% in the first 3 months up to 85% after 2 years. Also, comorbidity resolution rates were positive: 74% for type 2 diabetes mellitus and 96% for hypertension.

Safety of SADIS

The safety of SADIS was defined as the incidence rate of postoperative complications and nutritional deficiencies. Postoperative complications were low, diarrhea being the most common complication. Vitamin A, selenium, and iron deficiency were the most common nutritional deficiencies after SADIS. Moreover, a high prevalence of protein deficiency (34%) was observed. However, the currently high technical variability in the SADIS procedure influences outcomes on deficiencies. Further studies are required to determine the best SADIS procedure and assess the long-term effects after SADIS.

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Reference:

Shoar, S., Poliakin, L., Rubenstein, R. et al. OBES SURG (2018) 28: 104. https://doi.org/10.1007/s11695-017-2838-8

Link to full text: https://link.springer.com/article/10.1007%2Fs11695-017-2838-8